
Starring some of Hollywood’s greats, including Nicole Kidman and Jamie Lee Curtis, Scarpetta It makes headlines. The new Prime Video series, released on March 11, 2026, revolves around a forensic doctor who uncovers mysterious crimes using forensic technology.
Nicole Kidman – Dr. Kay Scarpetta
Nicole is one of the biggest names in the film industry. Having starred in countless films and television series, the Academy Award winner plays the title role, Dr. Kay Scarpetta, a brilliant forensic scientist who uses her expertise with technology to solve mysteries and crimes.
The Australian’s career gained momentum in the 1990s through her acting in films Far and away, to die for, Batman Forever, practical magic and Eyes wide closed. In 2002, Nicole won an Academy Award for her role in Virginia Woolf Watches. She also received nominations for her performance in Moulin Rouge!, The Rabbit Hole, The Lion and Being Ricardosin which I played Lucille Ball.
On television, Nicole has made a name for herself on the small screen through her acting Undo, Nine Perfect Strangers, Big Little Lies and The perfect couple.

Jamie Lee Curtis – Dorothy Scarpetta
Everyone should know Jamie because of her ultimate “The Final Girl” legacy Halloween franchise, but she has also made a name for herself in film and television through her acting Blue Steel, My Girl, Freaky Friday And as a continuation of it, Freaky Friday, Christmas with cranks, knives out, and everything everywhere at once and The last showgirl. Jamie won an Academy Award for Best Supporting Actress for her performance in the film Everything everywhere at once.
On television, she became known for her performances in Bear. In Scarpetta, Jamie plays Dorothy, Kay’s older sister.
Ariana DeBose – Lucy Farinelli Watson
Ariana DeBose She plays Lucy, Dorothy’s daughter, and the actress is a fine performer. In theatre, she is best known for… Hamilton, a Bronx tale and Summer: Donna’s Summer Musical. She then took her theatrical skills to hosting the Tony Awards several times.
Ariana also took her musical prowess to the screen by starring in the recent film adaptation West Side Story!
Bobby Cannavale – former detective Pete Marino
Bobby Cannavale Playing a former detective in the series, the actor has risen to stardom over the years. Bobby is best known for his television roles Will & GraceFor which he won an Emmy Award for Outstanding Guest Actor. Vinyl, Mr. Robot, The Blue Bloods, Homecoming, Nine Perfect Strangers and observer.
Simon Baker – FBI analyst Benton Wesley
Last but not least, Simon Baker He plays an FBI profiler in the show. The Australian native has been seen in a variety of film and television roles over the past 20 years, including The Guardian, which earned him a Golden Globe Award nomination for Outstanding Actor in a Television Series – Drama, and The Mentalist, which earned him an Emmy Award nomination.
Simon has also appeared in many films, including… Los Angeles Confidential, The Devil Wears Prada and Margin call.

